It’s about time! Quirky — to put it mildly — Comedy Central series The Sarah Silverman Program launches its long-awaited third season on Thursday, February 4, at 10:30pm ET.

First up during the ten-episode run is the season premiere, which has the undeniably charming title “The Proof Is in the Penis.”

Man-centric basic-cable network Spike TV has a brand-new original sitcom called Blue Mountain State premiering with two back-to-back episodes on January 12 at 10pm ET.

The series focuses on three freshmen football players at fictional Blue Mountain State college, who have to cope with girls, hazing, partying, and classes, in addition to playing a sport at the national level.

As hard as it is to believe that the comedy has been on that long, it’s indeed almost time to watch How I Met Your Mother’s landmark 100th episode. The accomplishment couldn’t have happened to a “nicer” sitcom, either.

The big event will occur at 8pm ET on Monday, January 11, which also happens to be the series’ first fresh episode of 2010. Called “Girls Vs. Suits,” it features a predictable slew of guest stars, too.

Mark those shiny new calendars, Entourage fans. The Emmy-winning HBO comedy is establishing a second home next week on the male-oriented basic-cable network Spike TV, which will begin airing the series in syndication on Tuesday, January 12, at 9pm ET.

It looks like Spike viewers can catch the show on Tuesdays during hourlong, back-to-back sessions, which will repeat afterwards at 11pm. There’s also even a chance that episodes will air in their original order, considering that premiere night will feature the pilot “Entourage” and the second episode “The Review.”

The second new December 27 episode of Fox’s Brothers is the first-season finale “Follow the Story,” which airs at 7:30pm ET.

Guest star Toni Trucks (All of Us, Barbershop) plays Meg, a sports magazine writer who visits the Trainors in Houston to write an in-depth article about Mike.

If you’ve been wondering whatever happened to the elusive Fox sitcom ‘Til Death, which is currently in its fourth season, wonder no more. After yet another prolonged absence, this one lasting just over two months, the comedy will return on Christmas Day for a two-hour, four-episode marathon.

According to Fox’s current schedule, the “Christmas present” will feature four brand-new episodes originally from the show’s second and third seasons: “No Complaints” at 8pm ET, “The Courtship of Eddie’s Parents” at 8:30pm, “The Ex-Factor” at 9pm, and “The Buffer” at 9:30pm.

Showtime’s Californication presents its third-season finale “Mia Culpa” on December 13.

As the hit comedy’s current run draws to a close, the Moody family prepares to relocate to the Big Apple.

FX’s newest original comedy The League closes its six-episode rookie season on December 10 with the finale “The Shiva Bowl.”

While Taco impresses by getting a “real” job…

It’s a fifth-season finale for the FX sitcom It’s Always Sunny in Philadelphia when it presents the new December 10 episode “The Gang Reignites the Rivalry.”

Scrooge types will be especially happy to hear that the finale doesn’t have a Christmas theme. Ah, sweet relief.

Yay! ABC’s Better Off Ted, one of my current favorite sitcoms, opens its second season on December 8 with the premiere “Love Blurts.”

Some folks who wouldn’t normally watch might want to tune in because the episode features guest star Taye Diggs of Private Practice and Day Break.